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Mastering the Chronic Constriction Injury Model

Mastering the Chronic Constriction Injury Model
Published Date: Thursday, 8 June 2023

 

The Eastern Mediterranean University (EMU) Faculty of Pharmacy takes great pride in recognizing the remarkable achievements of Nardin Sedghizadeh, a highly esteemed member of their faculty and a dedicated PhD student at Anadolu University Faculty of Pharmacy. Nardin's outstanding accomplishments extend beyond her academic pursuits, as she has gained invaluable practical experience at Anadolu University's Experimental Animal Laboratory, specializing in various techniques with remarkable success.

One of Nardin's notable areas of expertise lies in the application of the Chronic Constriction Injury (CCI) model, a method widely recognized for its significance in pain study research. The CCI model involves surgically inducing nerve damage in experimental animals to simulate chronic neuropathic pain conditions, allowing researchers to better understand the underlying mechanisms and potential therapeutic interventions

Undertaking the CCI method requires a high level of technical proficiency and meticulous attention to detail. Nardin's ability to master this complex procedure independently speaks volumes about her exceptional skills, unwavering dedication, and scientific acumen. By successfully conducting the CCI model, Nardin has demonstrated her comprehensive understanding of the intricacies involved in manipulating and interpreting experimental data associated with chronic pain.

The significance of the CCI model cannot be overstated in the field of pain research. It offers a valuable tool for investigating the pathophysiology of neuropathic pain, assessing the efficacy of novel analgesic compounds, and exploring potential therapeutic targets. The success of the CCI method lies in its ability to replicate the chronic and debilitating nature of neuropathic pain, enabling researchers to develop a deeper understanding of the underlying mechanisms and ultimately contribute to the development of more effective treatments.

 

Although the CCI model is considered a challenging technique due to the surgical procedure involved, its rewards are immeasurable. Researchers like Nardin, who have honed their skills and expertise in executing this intricate method, contribute significantly to the advancement of pain study research. Nardin's accomplishments in mastering the CCI model serve as a testament to her exceptional abilities, unwavering commitment, and invaluable contributions to the field of pharmaceutical research.

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